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Repayments of long-term lines of credit, gross Repayments Of Long-Term Lines Of Credit, Gross Repayments Of Long-Term Lines Of Credit, Gross Schedule of Concentrations of Credit Risk and Significant Customers Schedules of Concentration of Risk, by Risk Factor [Table Text Block] Underlying Securities Award Underlying Securities Amount Concentration Risk [Line Items] Concentration Risk [Line Items] Equity Component [Domain] Equity Component [Domain] Provision for excess inventory Provision For Excess Inventory Provision For Excess Inventory Document Period End Date Document Period End Date PEO Actually Paid Compensation Amount PEO Actually Paid Compensation Amount Cash and Cash Equivalents [Domain] Cash and Cash Equivalents [Domain] Cash, Cash Equivalents, Restricted Cash and Marketable Securities Cash, Cash Equivalent, and Marketable Security [Text Block] Awards Close in Time to MNPI Disclosures, Table Awards Close in Time to MNPI Disclosures [Table Text Block] Revenue from Contract with Customer [Abstract] Schedule of Investments [Table] Schedule of Investments [Table] Loan Facility, Tranche 1 Loan Facility, Tranche One [Member] Loan Facility, Tranche One Loan Facility Loan Facility [Member] Loan facility member. Document Type Document Type Number of non-option awards outstanding (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding, Number Name Outstanding Recovery, Individual Name Product and Service [Axis] Product and Service [Axis] Product revenue, net Revenue from Contract with Customer, Excluding Assessed Tax Collaborative Arrangement, Transaction with Party to Collaborative Arrangement Collaborative Arrangement, Transaction with Party to Collaborative Arrangement [Member] All Individuals All Individuals [Member] Long-Term Debt, Type [Domain] Long-Term Debt, Type [Domain] Purchases of property and equipment, net of disposals Payments to Acquire Property, Plant, and Equipment Name Forgone Recovery, Individual Name Expiration period (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period Total current assets Assets, Current Statistical Measurement [Axis] Statistical Measurement [Axis] Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member] Authorized capital Share Repurchase Program, Authorized, Amount Other clinical study related costs Accrued Other Clinical Study Related Costs Current Accrued other clinical study related costs current. Aggregate Erroneous Compensation Amount Aggregate Erroneous Compensation Amount Total intrinsic value of options exercised Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value Schedule Of Gross To Net Adjustments Reserve Schedule Of Gross To Net Adjustments Reserve [Table Text Block] Schedule Of Gross To Net Adjustments Reserve Peer Group Issuers, Footnote Peer Group Issuers, Footnote [Text Block] U.S. government and government sponsored entities due within 1 year of date of purchase (Level 2) US Treasury And Government Due Within One Year [Member] US Treasury And Government Due Within One Year Accrued Liabilities, Current [Abstract] Accrued Liabilities, Current [Abstract] Erroneous Compensation Analysis Erroneous Compensation Analysis [Text Block] Unrealized loss on marketable securities and foreign currency Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Current liabilities: Liabilities, Current [Abstract] Payments and customer credits issued Gross To Net Adjustments Reserve Credits And Payments Made Gross To Net Adjustments Reserve Credits And Payments Made Hercules Warrants Hercules Warrants [Member] Hercules Warrants Total operating expenses Operating Expenses Rule 10b5-1 Arrangement Terminated Rule 10b5-1 Arrangement Terminated [Flag] Accrued liabilities Increase (Decrease) in Accrued Liabilities Diluted net loss per common share (in dollars per share) Earnings Per Share, Diluted Erroneously Awarded Compensation Recovery Erroneously Awarded Compensation Recovery [Table] Trade receivables, net Accounts Receivable, after Allowance for Credit Loss, Current Concentration Risk Benchmark [Domain] Concentration Risk Benchmark [Domain] Title of 12(b) Security Title of 12(b) Security Other comprehensive income (loss): Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Number of shares issued in transaction (in shares) Sale of Stock, Number of Shares Issued in Transaction Stock-based compensation expense related to equity-classified awards APIC, Share-Based Payment Arrangement, Option, Increase for Cost Recognition Net loss per common share: Earnings Per Share [Abstract] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Marketable securities Debt Securities, Available-for-Sale, Current Comprehensive Income (Loss) Comprehensive Income, Policy [Policy Text Block] Accrued Liabilities Accounts Payable and Accrued Liabilities Disclosure [Text Block] Options exercised (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Collaborative Arrangement and Arrangement Other than Collaborative [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Award Timing Disclosures [Line Items] Schedule of Inventory Schedule of Inventory, Current [Table Text Block] Long-term debt Long-Term Debt, Gross Options granted (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Variable Rate Component [Axis] Variable Rate Component [Axis] Variable Rate Component Compensation and benefits Employee-related Liabilities, Current Stockholders' Equity Equity [Text Block] Line of credit facility, current borrowing capacity Line of Credit Facility, Current Borrowing Capacity Net loss Net loss Net loss Net loss Net Income (Loss) Attributable to Parent Subsequent Event [Table] Subsequent Event [Table] Expiration Date Trading Arrangement Expiration Date Long term liabilities: Liabilities, Noncurrent [Abstract] 2025 Inducement Plan Inducement Plan 2025 [Member] Inducement Plan 2025 Other Other Accrued Liabilities, Current Remainder of future milestone payments Remaining Milestone Payments The amount of future milestone payments remaining to be paid under the agreement. Property and equipment, net Property, Plant and Equipment, Net Segment Reporting Information [Line Items] Segment Reporting Information [Line Items] Preferred stock, shares authorized (in shares) Preferred Stock, Shares Authorized Adoption Date Trading Arrangement Adoption Date Compensation Actually Paid vs. Net Income Compensation Actually Paid vs. Net Income [Text Block] Trade receivables, net Increase (Decrease) in Accounts Receivable Inventory Inventory, Policy [Policy Text Block] Entity Current Reporting Status Entity Current Reporting Status Customer [Axis] Customer [Axis] Selling, General and Administrative Expenses Selling, General and Administrative Expenses, Policy [Policy Text Block] Awards Close in Time to MNPI Disclosures Awards Close in Time to MNPI Disclosures [Table] Loss from operations Operating Income (Loss) Loan Facility, Tranche 2 Loan Facility, Tranche Two [Member] Loan Facility, Tranche Two Line of Credit Line of Credit [Member] Accumulated deficit Accumulated deficit Retained Earnings (Accumulated Deficit) Financial Instrument [Axis] Financial Instrument [Axis] Beneficial ownership maximum percentage Class Of Warrant Or Right, Beneficial Ownership, Maximum Threshold Class Of Warrant Or Right, Beneficial Ownership, Maximum Threshold Statement of Financial Position [Abstract] Statement of Financial Position [Abstract] Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member] Executive Category: Executive Category [Axis] Class of Stock [Axis] Class of Stock [Axis] Current Fiscal Year End Date Current Fiscal Year End Date Balance, beginning Balance, ending Gross To Net Adjustments Reserve Gross To Net Adjustments Reserve Subsequent Event Type [Domain] Subsequent Event Type [Domain] Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member] Weighted average grant date fair value Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract] Shares available for future issuance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Statement [Table] Statement [Table] Other expense Other Nonoperating Income (Expense) US government and government sponsored entities due within 1 to 2 years of date of purchase (Level 2) US Treasury And Government Due Within One To Two Years [Member] US Treasury And Government Due Within One To Two Years Adjustments to reconcile net loss to net cash used in operating activities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract] Cash flows from financing activities: Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Weighted-average grant date fair value of options (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Cash Cash [Member] Equity Awards Adjustments, Excluding Value Reported in Compensation Table Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member] Organization, Business, and Basis of Presentation Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] Cash and Cash Equivalents [Abstract] Cash and Cash Equivalents [Abstract] Antidilutive securities excluded from computation of earnings per share (in shares) Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount All Adjustments to Compensation All Adjustments to Compensation [Member] Amendment Flag Amendment Flag Shares issued (in dollars per share) Sale of Stock, Price Per Share CSPC CSPC Pharmaceutical Group Limited [Member] CSPC Pharmaceutical Group Limited 2027 Long-Term Debt, Maturity, Year Two Termination Date Trading Arrangement Termination Date Net cash provided by financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Contract research organization costs Accrued Contract Research Costs Current Accrued Contract Research Costs, Current. Insider Trading Policies and Procedures Adopted Insider Trading Policies and Procedures Adopted [Flag] Accrued interest, net of interest received on maturity of investments Increase (Decrease) In Accrued Interest, Net Of Interest Received The increase (decrease) during the reporting period in the aggregate amount of accrued interest expense incurred but not yet paid, net of interest received on maturity of investments. Measure: Measure [Axis] Raw materials Inventory, Raw Materials, Net of Reserves Schedule of Stock Option Activity Share-Based Payment Arrangement, Option, Activity [Table Text Block] Basic weighted average number of common shares outstanding (in shares) Weighted Average Number of Shares Outstanding, Basic Warrants and rights outstanding Warrants and Rights Outstanding Maximum aggregate offering price Common Stock Aggregate Offering Price Represents the maximum aggregate offering price the entity may issue and sell shares of its common stock from time to time, at the entity's option, according to at-the-market issuance sales agreement with third party. Exercisable at the ending of the year (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Two Thousand and Twenty Two Registered Direct Offering Two Thousand and Twenty Two Registered Direct Offering [Member] Two Thousand and Twenty Two Registered Direct Offering [Member] Subsequent Events [Abstract] Subsequent Events [Abstract] Segment Reporting [Abstract] Pay vs Performance Disclosure, Table Pay vs Performance [Table Text Block] Debt Disclosure [Abstract] Debt Disclosure [Abstract] Forgone Recovery due to Violation of Home Country Law, Amount Forgone Recovery due to Violation of Home Country Law, Amount Entity Tax Identification Number Entity Tax Identification Number Pre-funded warrants Pre Funded Warrants [Member] Pre FundedWarrants [Member] Operating expenses: Costs and Expenses [Abstract] Line of credit facility, decrease In maximum borrowing capacity Line Of Credit Facility, Decrease In Maximum Borrowing Capacity Line Of Credit Facility, Decrease In Maximum Borrowing Capacity Less unamortized discount Debt Instrument, Unamortized Discount Outstanding at the beginning of the year (in dollars per share) Outstanding at the ending of the year (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Minimum unrestricted cash balance Debt Instrument, Covenant, Unrestricted Cash, Minimum Debt Instrument, Covenant, Unrestricted Cash, Minimum Forgone Recovery due to Expense of Enforcement, Amount Forgone Recovery due to Expense of Enforcement, Amount Unrecognized stock-based compensation expense Stock-based compensation expense Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Common stock, par value (in dollars per share) Common Stock, Par or Stated Value Per Share Common stock, shares issued (in shares) Balance (in shares) Balance (in shares) Common Stock, Shares, Issued Options granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Use of Estimates Use of Estimates, Policy [Policy Text Block] Interest expense Interest Expense, Nonoperating Trading Arrangement: Trading Arrangement [Axis] Total Shareholder Return Amount Total Shareholder Return Amount Subsequent Events Subsequent Events [Text Block] Insider Trading Arrangements [Line Items] Security Exchange Name Security Exchange Name Options cancelled (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Customer C Customers C [Member] Customers C Shares Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding [Roll Forward] Variable Rate Component [Domain] Variable Rate Component [Domain] Variable Rate Component [Domain] 2025 Long-Term Debt, Maturity, Remainder of Fiscal Year Total long term liabilities Liabilities, Noncurrent Total liabilities Liabilities Cash and Cash Equivalents [Axis] Cash and Cash Equivalents [Axis] Antidilutive Securities, Name [Domain] Antidilutive Securities, Name [Domain] Term charges on aggregate principal amount, (as a percent) Line of Credit Facility, Commitment Fee Percentage Additional drawn Line of Credit Facility, Maximum Borrowing Capacity Pension Adjustments Prior Service Cost Pension Adjustments Prior Service Cost [Member] Sales and maturities of marketable securities Proceeds from Sale and Maturity of Debt Securities, Available-for-Sale Material Terms of Trading Arrangement Material Terms of Trading Arrangement [Text Block] Preferred shares number voting rights Preferred Stock, Number Of Voting Rights Number of voting rights of preferred stock. Includes eligibility to vote and votes per share owned. Include also, if any, unusual voting rights. Customer D Customers D [Member] Customers D 2024 Sales Agreement 2024 Sales Agreement [Member] 2024 Sales Agreement Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs Stock Issued During Period, Value, New Issues Statement Statement [Line Items] Rule 10b5-1 Arrangement Adopted Rule 10b5-1 Arrangement Adopted [Flag] Cash and cash equivalents Cash and Cash Equivalent Counterparty Name [Axis] Counterparty Name [Axis] Subsequent Event [Line Items] Subsequent Event [Line Items] Common stock Common Stock [Member] RSUs vested (in shares) PSUs attained (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Fair value Debt Securities, Available-for-Sale Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Non-NEOs Non-NEOs [Member] Corporate Debt Securities Corporate Debt Securities [Member] Net increase in cash, cash equivalents, and restricted cash Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation Professional fees Accrued Professional Fees, Current