SECURITIES AND EXCHANGE COMMISSION
		     	     Washington, D.C. 20549

			          SCHEDULE 13D
		      Under the Securities Exchange Act of 1934

				(Amendment No. 1)

		     	    Synta Pharmaceuticals Corp.
		       		 (Name of Issuer)

			  	   Common Stock
		 	  (Title of Class of Securities)

				    87162T206
			          (CUSIP Number)

			     Mr. Scott B. Bernstein
			       Caxton Corporation
			   731 Alexander Road, Bldg. 2
			   Princeton, New Jersey 08540
			         (609) 419-1800
          (Name, Address and Telephone Number of Person Authorized to
                       Receive Notices and Communications)

			  	    1/8/2010
             (Date of Event which Requires Filing of this Statement)


If the filing person has previously filed a statement on Schedule 13G to
report the acquisition that is the subject of this Schedule 13D, and is
filing this schedule because of Section 240.13d-1(e), 240.13d-1(f) or
240.13d-1(g), check the following box. | |

Note:  Schedules filed in paper format shall include a signed original and
five copies of the schedule, including all exhibits.  See Section
240.13d-7 for other parties to whom copies are to be sent.

*The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class
of securities, and for any subsequent amendment containing information
which would alter disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be
deemed to be "filed" for the purpose of Section 18 of the Securities Exchange
Act of 1934 ("Act") or otherwise subject to the liabilities of that section of
the Act but shall be subject to all other provisions of the Act (however, see
the Notes).


 (1) Names of Reporting Persons.
     I.R.S. Identification Nos. of above persons (entities only).

    CxSynta LLC
    02-0604347

 (2) Check the Appropriate Box if a Member of a Group (See Instructions)  (a)|_|
                                                                          (b)|x|

 (3) SEC Use Only.

 (4) Source of Funds (See Instructions).
    WC

 (5) Check if Disclosure of Legal Proceedings is Required Pursuant to Items
     2(d) or 2(e)  |_|

 (6) Citizenship or Place of Organization
    Delaware

Number of Shares Beneficially Owned by Each Reporting Person With:

 (7) Sole Voting Power:
    0

 (8) Shared Voting Power:
    7,761,716

 (9) Sole Dispositive Power:
    0

 (10) Shared Dispositive Power:
    7,761,716

 (11) Aggregate Amount Beneficially Owned by Each Reporting Person.
    7,761,716

 (12) Check if the Aggregate Amount in Row (11) Excludes Certain Shares
      (see instructions).  |_|

 (13) Percent of Class Represented by Amount in Row (11).
     19.6%

 (14) Type of Reporting Person (See Instructions).
     OO

(1) Names of Reporting Persons.
     I.R.S. Identification Nos. of above persons (entities only).

    Caxton Corporation
    22-2437619

 (2) Check the Appropriate Box if a Member of a Group (See Instructions)  (a)|_|
                                                                          (b)|x|

 (3) SEC Use Only.

 (4) Source of Funds (See Instructions).
    AF

 (5) Check if Disclosure of Legal Proceedings is Required Pursuant to Items
     2(d) or 2(e)  |_|

 (6) Citizenship or Place of Organization
    Delaware

Number of Shares Beneficially Owned by Each Reporting Person With:

 (7) Sole Voting Power:
    0

 (8) Shared Voting Power:
    7,761,716

 (9) Sole Dispositive Power:
    0

 (10) Shared Dispositive Power:
    7,761,716

 (11) Aggregate Amount Beneficially Owned by Each Reporting Person.
    7,761,716

 (12) Check if the Aggregate Amount in Row (11) Excludes Certain Shares
      (see instructions).  |_|

 (13) Percent of Class Represented by Amount in Row (11).
     19.6%

 (14) Type of Reporting Person (See Instructions).
    CO

 (1) Names of Reporting Persons.
     I.R.S. Identification Nos. of above persons (entities only).

    Kovner, Bruce

 (2) Check the Appropriate Box if a Member of a Group (See Instructions)  (a)|_|
                                                                          (b)|x|

 (3) SEC Use Only.

 (4) Source of Funds (See Instructions).
    AF,PF

 (5) Check if Disclosure of Legal Proceedings is Required Pursuant to Items
     2(d) or 2(e)  |_|

 (6) Citizenship or Place of Organization
    United States

Number of Shares Beneficially Owned by Each Reporting Person With:

 (7) Sole Voting Power:
    1,563,610

 (8) Shared Voting Power:
    7,761,716

 (9) Sole Dispositive Power:
    1,563,610

 (10) Shared Dispositive Power:
    7,761,716

 (11) Aggregate Amount Beneficially Owned by Each Reporting Person.
    9,325,326

 (12) Check if the Aggregate Amount in Row (11) Excludes Certain Shares
      (see instructions).  |_|

 (13) Percent of Class Represented by Amount in Row (11).
     23.6%

 (14) Type of Reporting Person (See Instructions).
     IN


Item 2.  Identity and Background

     Subparagraph (c) of Item 2 of the Schedule 13D is hereby amended and
     replaced by the following:

(c)
     (i) The principal business of CxSynta is to serve primarily as an
     investment vehicle for investment in the securities of the Company.

     (ii) The principal business of Caxton Corporation is serving as
     general partner of Caxton Associates LP.

     (iii) The present principal occupation of Mr. Kovner is Chairman of
      Caxton Associates LP. The address of Caxton Associates LP,
      is 731 Alexander Road, Bldg. 2 Princeton, NJ 0854


Item 3.  Source and Amount of Funds or Other Consideration

     Item 3 is hereby amended by adding the following thereto:

     Mr. Kovner has expended an aggregate of approximately $11,611,932
     (excluding commissions, if any) to acquire the 1,563,610 shares of
     Common Stock directly owned by him.  The purchase price for the
     shares of Common Stock acquired by Mr. Kovner was paid out of Mr.
     Kovner's personal funds.


Item 5.  Interest in Securities of the Issuer

     Subparagraph (a), (b) and (c) of Item 5 of the Schedule 13D is
     hereby amended and replaced by the following:

(a)  (i) CxSynta beneficially owns 7,761,716 shares
      of Common Stock, representing approximately 19.6% of the 39,533,856
      shares of Common Stock reported to be outstanding as of January 13,
      2010, as reported in the Company's Prospectus filed with the Securities
      Exchange Commission on Form 424B5 on January 8, 2010 (the "Company's
      Prospectus"). The percentages used herein and in the rest of this
      Amendment No. 1 are calculated based upon such number of outstanding
      shares.

     (ii) Caxton Corporation is the managing member of CxSynta and as such,
      has voting and dispositive power with respect to the shares beneficially
      owned by CxSynta.  As a result, Caxton Corporation maybe deemed to
      beneficially own 7,761,716 shares of Common Stock, representing
      approximately 19.6% of the total shares of Common Stock issued
      and outstanding.

     (iii) Mr. Kovner has sole beneficial ownership of 1,563,610 shares of
      Common Stock, which includes options to purchase 62,937 shares of Common
      Stock upon the exercise of such options.  In addition, Mr. Kovner is the
      Chairman and sole shareholder of Caxton Corporation and as a result may
      be deemed to beneficially own the securities of the Company owned by
      CxSynta.  Mr. Kovner disclaims beneficial ownership of the shares of
      Common Stock owned directly by CxSynta except to the extent of his
      pecuniary interest therein. As a result of the foregoing, Mr. Kovner
      may be deemed to beneficially own an aggregate of 9,325,326 shares of
      Common Stock, representing approximately 23.6% of the total shares of
      Common Stock issued and outstanding.

(b)   Caxton Corporation and Mr. Kovner may be deemed to share voting and
      dispositive power over the 7,761,716 shares of Common Stock owned
      directly by CxSynta.   In addition, Mr. Kovner has sole
      voting and dispositive power with respect to the 1,563,610 shares of
      Common Stock which he directly beneficially owns.

(c)  On January 8, 2010, Mr. Kovner purchased 550,000 shares of Common Stock
     at a price of approximately $4.50 per share from Lazard Capital Markets
     LLC, the underwriters for the Company's Offering of Common Stock (the
     "Company's Offering"). Such shares were purchased pursuant to the terms
     of the Company's Prospectus.

     In addition, as referenced in Item 6 of this Amendment, Mr. Kovner
     received a grant of 5500 options to purchase shares of Common Stock of
     which 1,375 of these options vested on each of September 30, 2009 and
     December 31, 2009.

     Except as reported in this statement on Schedule 13D, the Reporting
     Persons have not engaged in any other transactions in the Company's
     securities in the past sixty (60) days.


Item 6.  Contracts, Arrangements, Understandings or Relationships
         with Respect to Securities of the Issuer.

     Item 6 is hereby amended by adding the following thereto:

     In connection with the Company's Offering of Common Stock, CxSynta and
     Mr. Kovner subject to certain exceptions, have agreed with Lazard
     Capital Markets LLC not to dispose of or hedge any of shares of the
     Company's Common Stock or securities convertible into or exercisable or
     exchangeable for Common Stock for 90 days after the date of the
     Company's Prospectus without first obtaining the written consent of
     Lazard Capital Markets LLC.

     In addition, in July 2009 in connection with his service as a Director
     of the Company, Mr. Kovner received a grant of 5500 options to purchase
     Common Stock at an exercise price of approximately $2.38.  The options
     expire on July 1, 2019 and 25% of the options vested on each of September
     30, 2009 and December 31, 2009, and 25% will vest on each of March 31,
     2010 and June 30, 2010 provided that Mr. Kovner continues to serve as a
     Director of the Company on such date.

     Except as set forth above, there are no contracts, arrangements,
     understandings or relationships (legal or otherwise) among the persons
     filing this Report or the Listed Persons or between such persons and
     any other person with respect to any securities of the Company, including,
     but not limited to transfer or voting of any of the securities, finder's
     fees, joint ventures, loan or option arrangements, puts or calls,
     guarantees of profits, division of profits or losses, or the giving or
     with-holding of proxies.

Item 7.  Material to Be Filed as Exhibits

     Item 7 is hereby amended and replaced with the following:

     The following are filed as Exhibits to this statement on Schedule 13D:

     Exhibit 1 - Form Lock-Up Agreement (The Form Lock-Up Agreement is
     filed as Exhibit 1 and is incorporated herein by reference to Exhibit
     A of Exhibit 1.1 to the Company's 8-K filed with the Securities and
     Exchange Commission on January 8, 2010.)


Signature


After reasonable inquiry and to the best of my knowledge and belief, I certify
that the information set forth in this statement is true, complete and correct.

					CxSynta LLC

Date: 1/12/2010				By Caxton Corporation, Managing Member
	                                of CxSynta LLC,
                                        by /s/ Scott B. Bernstein,
					Secretary of Caxton Corporation

					Caxton Corporation

Date: 1/12/2010				/s/ Scott B. Bernstein, Secretary of
					Caxton Corporation


					Bruce S. Kovner
Date: 1/12/2010				/s/ Scott B. Bernstein, Attorney-in-Fact



The original statement shall be signed by each person on whose behalf the
statement is filed or his authorized representative. If the statement is
signed on behalf of a person by his authorized representative (other than
an executive officer or general partner of the filing person), evidence of
the representative's authority to sign on behalf of such person shall be
filed with the statement: provided, however, that a power of attorney for
this purpose which is already on file with the Commission may be incorporated
by reference.  The name and any title of each person who signs the statement
shall be typed or printed beneath his signature.

ATTENTION: Intentional misstatements or omissions of fact constitute Federal
criminal violations (See 18 U.S.C. 1001).