SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person* CxSynta LLC (Last) (First) (Middle) C/O CAXTON CORPORATION 731 ALEXANDER ROAD, BUILDING 2 (Street) PRINCETON NJ 08540 (City) (State) (Zip)	2. Date of Event Requiring Statement (Month/Day/Year) 02/05/2007	3. Issuer Name and Ticker or Trading Symbol SYNTA PHARMACEUTICALS CORP [ SNTA ]
		4. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director X 10% Owner Officer (give title below) Other (specify below)	5. If Amendment, Date of Original Filed (Month/Day/Year)
			6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person X Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	6,071,070(1)	D(2)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Series A Convertible Preferred Stock	(3)	(4)	Common Stock	2,154,105(3)	(3)	D(2)

1. Name and Address of Reporting Person* CxSynta LLC (Last) (First) (Middle) C/O CAXTON CORPORATION 731 ALEXANDER ROAD, BUILDING 2 (Street) PRINCETON NJ 08540 (City) (State) (Zip)

1. Name and Address of Reporting Person* CAXTON CORP (Last) (First) (Middle) 731 ALEXANDER ROAD, BUILDING 2 (Street) PRINCETON NJ 08540 (City) (State) (Zip)

Explanation of Responses:

1. Reflects a 1-for-4 reverse stock split effected on February 2, 2007 in connection with the Issuer's initial public offering, pursuant to which the number of shares of Common Stock was divided by 4.

2. These shares are directly owned by CxSynta LLC and indirectly owned by Caxton Corporation, the managing member of CxSynta LLC.

3. Upon the closing of the Issuer's initial public offering of Common Stock, each share of Series A Convertible Preferred Stock, plus accrued dividends, will convert into a certain number of shares of Common Stock in accordance with the terms of the Issuer's Restated Certificate of Incorporation, as amended.

4. N/A.

	By Caxton Corporation, Managing Member of CxSynta LLC, by /s/ Scott B. Bernstein, Secretary of Caxton Corporation	02/05/2007
	/s/ Scott B. Bernstein, Secretary of Caxton Corporation	02/05/2007
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
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